Schizoaffective psychoses: Genetical clues to classification

A. Bertelsen, Irving I Gottesman

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


The diagnostic classification of schizoaffective psychoses has varied much since Kasanin introduced the concept in 1933. The various classifications have agreed that schizoaffective psychoses present a combination of schizophreniform and affective symptoms, but the diagnostic criteria differ as to the number, quality, and time sequence of the symptoms even in recent classifications like RDC, DSM-III-R, and ICD-10. The classifications are syndromatical, and the etiology of the schizoaffective psychoses is still undetermined apart from evidence for a strong genetic factor. Results from family, twin, and adoption studies are divergent, but all the same, support a separate classification of broadly defined schizoaffective psychoses as possibly being phenotypical variations or expressions of genetic inter-forms between schizophrenia and affective psychoses.

Original languageEnglish (US)
Pages (from-to)7-11
Number of pages5
JournalAmerican Journal of Medical Genetics - Neuropsychiatric Genetics
Issue number1
StatePublished - Mar 13 1995


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