Screening Donated Blood and Plasma for HTLV-III Antibody: Facing More Than One Crisis?

Michael T. Osterholm; Robert J. Bowman; Michael W. Chopek; J. Jeffrey Mccullough; Jack A. Korlath; Herbert F. Polesky

doi:10.1056/NEJM198505023121810

Screening Donated Blood and Plasma for HTLV-III Antibody: Facing More Than One Crisis?

Michael T. Osterholm, Robert J. Bowman, Michael W. Chopek, J. Jeffrey Mccullough, Jack A. Korlath, Herbert F. Polesky

Research output: Contribution to journal › Editorial › peer-review

29 Scopus citations

Abstract

Little question remains that the causative agent of the acquired immunodeficiency syndrome (AIDS) is the newly recognized retrovirus, human T-cell lymphotropic virus Type III (HTLV-III).¹ ² ³ ⁴ ⁵ AIDS, the AIDS-related complex, and asymptomatic HTLV-III infection have been associated with several well-defined high-risk groups, including recipients of blood and blood products.⁶ ⁷ ⁸ Protection of our nation's blood and plasma supply from HTLV-III contamination has been one of the highest public health priorities related to the AIDS epidemic. Studies of symptomatic and asymptomatic members of high-risk groups indicate that those who are infected with HTLV-III are also likely to be positive for HTLV-III antibody.³^,⁹ ¹⁰ ¹¹ Tests.

Original language	English (US)
Pages (from-to)	1185-1189
Number of pages	5
Journal	New England Journal of Medicine
Volume	312
Issue number	18
DOIs	https://doi.org/10.1056/NEJM198505023121810
State	Published - May 2 1985

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@article{c8ea3598834f4d7ebe763af9af792880,

title = "Screening Donated Blood and Plasma for HTLV-III Antibody: Facing More Than One Crisis?",

abstract = "Little question remains that the causative agent of the acquired immunodeficiency syndrome (AIDS) is the newly recognized retrovirus, human T-cell lymphotropic virus Type III (HTLV-III).1 2 3 4 5 AIDS, the AIDS-related complex, and asymptomatic HTLV-III infection have been associated with several well-defined high-risk groups, including recipients of blood and blood products.6 7 8 Protection of our nation's blood and plasma supply from HTLV-III contamination has been one of the highest public health priorities related to the AIDS epidemic. Studies of symptomatic and asymptomatic members of high-risk groups indicate that those who are infected with HTLV-III are also likely to be positive for HTLV-III antibody.3,9 10 11 Tests.",

author = "Osterholm, {Michael T.} and Bowman, {Robert J.} and Chopek, {Michael W.} and Mccullough, {J. Jeffrey} and Korlath, {Jack A.} and Polesky, {Herbert F.}",

year = "1985",

month = may,

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doi = "10.1056/NEJM198505023121810",

language = "English (US)",

volume = "312",

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journal = "New England Journal of Medicine",

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T1 - Screening Donated Blood and Plasma for HTLV-III Antibody

T2 - Facing More Than One Crisis?

AU - Osterholm, Michael T.

AU - Bowman, Robert J.

AU - Chopek, Michael W.

AU - Mccullough, J. Jeffrey

AU - Korlath, Jack A.

AU - Polesky, Herbert F.

PY - 1985/5/2

Y1 - 1985/5/2

N2 - Little question remains that the causative agent of the acquired immunodeficiency syndrome (AIDS) is the newly recognized retrovirus, human T-cell lymphotropic virus Type III (HTLV-III).1 2 3 4 5 AIDS, the AIDS-related complex, and asymptomatic HTLV-III infection have been associated with several well-defined high-risk groups, including recipients of blood and blood products.6 7 8 Protection of our nation's blood and plasma supply from HTLV-III contamination has been one of the highest public health priorities related to the AIDS epidemic. Studies of symptomatic and asymptomatic members of high-risk groups indicate that those who are infected with HTLV-III are also likely to be positive for HTLV-III antibody.3,9 10 11 Tests.

AB - Little question remains that the causative agent of the acquired immunodeficiency syndrome (AIDS) is the newly recognized retrovirus, human T-cell lymphotropic virus Type III (HTLV-III).1 2 3 4 5 AIDS, the AIDS-related complex, and asymptomatic HTLV-III infection have been associated with several well-defined high-risk groups, including recipients of blood and blood products.6 7 8 Protection of our nation's blood and plasma supply from HTLV-III contamination has been one of the highest public health priorities related to the AIDS epidemic. Studies of symptomatic and asymptomatic members of high-risk groups indicate that those who are infected with HTLV-III are also likely to be positive for HTLV-III antibody.3,9 10 11 Tests.

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