Screening for Colorectal Cancer

David A. Ahlquist; Charles G. Moertel; Douglas B. Mcgill; William D. Carey; Edgar Achkar; Robert Perlman; Brian Budenholzer; Alfred I. Neugut; Judith S. Jacobson; James E. Allison; Martin L. Brown; Jack S. Mandel; Timothy R. Church; Fred Ederer; Sidney J. Winawer

doi:10.1056/NEJM199310283291813

Screening for Colorectal Cancer

David A. Ahlquist, Charles G. Moertel, Douglas B. Mcgill, William D. Carey, Edgar Achkar, Robert Perlman, Brian Budenholzer, Alfred I. Neugut, Judith S. Jacobson, James E. Allison, Martin L. Brown, Jack S. Mandel, Timothy R. Church, Fred Ederer, Sidney J. Winawer

Environmental Health Sciences

Research output: Contribution to journal › Letter › peer-review

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Abstract

To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)¹. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to…

Original language	English (US)
Pages (from-to)	1351-1354
Number of pages	4
Journal	New England Journal of Medicine
Volume	329
Issue number	18
DOIs	https://doi.org/10.1056/NEJM199310283291813
State	Published - Oct 28 1993

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title = "Screening for Colorectal Cancer",

abstract = "To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)1. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to…",

author = "Ahlquist, {David A.} and Moertel, {Charles G.} and Mcgill, {Douglas B.} and Carey, {William D.} and Edgar Achkar and Robert Perlman and Brian Budenholzer and Neugut, {Alfred I.} and Jacobson, {Judith S.} and Allison, {James E.} and Brown, {Martin L.} and Mandel, {Jack S.} and Church, {Timothy R.} and Fred Ederer and Winawer, {Sidney J.}",

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AU - Ahlquist, David A.

AU - Moertel, Charles G.

AU - Mcgill, Douglas B.

AU - Carey, William D.

AU - Achkar, Edgar

AU - Perlman, Robert

AU - Budenholzer, Brian

AU - Neugut, Alfred I.

AU - Jacobson, Judith S.

AU - Allison, James E.

AU - Brown, Martin L.

AU - Mandel, Jack S.

AU - Church, Timothy R.

AU - Ederer, Fred

AU - Winawer, Sidney J.

PY - 1993/10/28

Y1 - 1993/10/28

N2 - To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)1. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to…

AB - To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)1. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to…

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Screening for Colorectal Cancer

Abstract

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