Semiphenomenological model for the dispersion of DNA during electrophoresis in a microfluidic array of posts

Kevin D. Dorfman, Jean Louis Viovy

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

A model for quantifying the dispersion of DNA during electrophoresis in a microfluidic array of posts was analyzed. The model was based on Monte Carlo method for simulating the dynamics of DNA motion and dispersion through the array. The trapping time, collision probability and post geometry were some of the parameters considered for the analytical model. The semiphenomenological model also aided in analysis of the separation process.

Original languageEnglish (US)
Article number011901
Pages (from-to)119011-119016
Number of pages6
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume69
Issue number1
DOIs
StatePublished - Jan 2004

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