Separate Cardiovascular disease risks: Circardian hyper-amplitude-tension (chta) and an elevated pulse pressure

Germaine G Cornelissen-Guillaume, Franz Halberg, Kuniaki Otsuka, Ram B. Singh

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Prospective data from 297 patients, interpreted in the context of outcomes on >2,750 patients providing >140,000 measurements, assess relative risks (RR) of elevated pulse pressure (EPP), diastolic CHAT, and decreased heart rate variability (DHRV), singly or combined. Cardiovascular morbidity assessed every 6 months for 6 years is increased in association with each risk factor. Risk is higher when EPP and D-CHAT coexist or when all three conditions are present than when D-CHAT, EPP, or DHRV is present singly. That EPP, D-CHAT and DHRV are to some degree additive deserves further scrutiny on larger samples.

Original languageEnglish (US)
Pages (from-to)223-232
Number of pages10
JournalWorld Heart Journal
Volume1
Issue number3
StatePublished - 2008

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