Separation of racemic 2,4-dinitrophenyl amino acids on carboxymethyl-β-cyclodextrin coated zirconia in RPLC

Sung Yeh Park; Jung Kon Park; Jung Hag Park; Clayton V. McNeff; Peter W. Carr

doi:10.1016/S0026-265X(01)00129-1

Separation of racemic 2,4-dinitrophenyl amino acids on carboxymethyl-β-cyclodextrin coated zirconia in RPLC

Sung Yeh Park, Jung Kon Park, Jung Hag Park, Clayton V. McNeff, Peter W. Carr

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

We report preparation and use of carboxymethyl-β-cyclodextrin-coated zirconia as a chiral stationary phase (CSP) for separation of enantiomers of 2,4-dinitrophenyl (DNP) amino acids in reversed-phase high performance liquid chromatography. The CSP showed good enantioselectivity for some of the amino acids studied. Effects of pH and amount of methanol in mobile phases on retention and enantioselectivity for the analytes were examined.

Original language	English (US)
Pages (from-to)	179-185
Number of pages	7
Journal	Microchemical Journal
Volume	70
Issue number	3
DOIs	https://doi.org/10.1016/S0026-265X(01)00129-1
State	Published - 2001

Bibliographical note

Funding Information:
This work was supported in part by a grant from the Korea Science and Engineering Foundation (2000-2-12400-001-3), in part by a grant from the Korea Research Foundation (1998-015-D00294) and in part by a grant from Yeungnam University (1999).

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

Carboxymethyl-β-cyclodextrin-coated zirconia
Chiral stationary phase, LC
RPLC separation
Racemic DNP-amino acids

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title = "Separation of racemic 2,4-dinitrophenyl amino acids on carboxymethyl-β-cyclodextrin coated zirconia in RPLC",

abstract = "We report preparation and use of carboxymethyl-β-cyclodextrin-coated zirconia as a chiral stationary phase (CSP) for separation of enantiomers of 2,4-dinitrophenyl (DNP) amino acids in reversed-phase high performance liquid chromatography. The CSP showed good enantioselectivity for some of the amino acids studied. Effects of pH and amount of methanol in mobile phases on retention and enantioselectivity for the analytes were examined.",

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note = "Funding Information: This work was supported in part by a grant from the Korea Science and Engineering Foundation (2000-2-12400-001-3), in part by a grant from the Korea Research Foundation (1998-015-D00294) and in part by a grant from Yeungnam University (1999). Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

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AU - Park, Jung Kon

AU - Park, Jung Hag

AU - McNeff, Clayton V.

AU - Carr, Peter W.

N1 - Funding Information: This work was supported in part by a grant from the Korea Science and Engineering Foundation (2000-2-12400-001-3), in part by a grant from the Korea Research Foundation (1998-015-D00294) and in part by a grant from Yeungnam University (1999). Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2001

Y1 - 2001

N2 - We report preparation and use of carboxymethyl-β-cyclodextrin-coated zirconia as a chiral stationary phase (CSP) for separation of enantiomers of 2,4-dinitrophenyl (DNP) amino acids in reversed-phase high performance liquid chromatography. The CSP showed good enantioselectivity for some of the amino acids studied. Effects of pH and amount of methanol in mobile phases on retention and enantioselectivity for the analytes were examined.

AB - We report preparation and use of carboxymethyl-β-cyclodextrin-coated zirconia as a chiral stationary phase (CSP) for separation of enantiomers of 2,4-dinitrophenyl (DNP) amino acids in reversed-phase high performance liquid chromatography. The CSP showed good enantioselectivity for some of the amino acids studied. Effects of pH and amount of methanol in mobile phases on retention and enantioselectivity for the analytes were examined.

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Separation of racemic 2,4-dinitrophenyl amino acids on carboxymethyl-β-cyclodextrin coated zirconia in RPLC

Abstract

Bibliographical note

Keywords

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