Sepsis-Induced Tissue Hypoperfusion

Alan E. Jones, Michael A. Puskarich

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Sepsis affects the cardiovascular system through multiple mechanisms, and often these derangements result in tissue hypoperfusion. Tissue hypoperfusion is often present in the setting of overt shock, but it can also be present in patients without obvious shock physiology. If left untreated, tissue hypoperfusion contributes to the development of multiple organ dysfunction and, ultimately, death. Therefore, it is critical for the clinician to understand the pathophysiology, recognition, and treatment of sepsis-induced hypoperfusion.

Original languageEnglish (US)
Pages (from-to)769-779
Number of pages11
JournalCritical Care Clinics
Issue number4
StatePublished - Oct 1 2009
Externally publishedYes


  • Emergency
  • Hypoperfusion
  • Infection
  • Lactate
  • Resuscitation
  • Sepsis
  • Septic shock

Fingerprint Dive into the research topics of 'Sepsis-Induced Tissue Hypoperfusion'. Together they form a unique fingerprint.

Cite this