Sequence distribution of acetaldehyde-derived N²-Ethyl-dG Adducts along Duplex DNA

Medicine & Life Sciences

• N2-ethyl-2'-deoxyguanosine 100%
• Acetaldehyde 58%
• N2-ethylidene-2'-deoxyguanosine 25%
• DNA 25%
• cytidylyl-3'-5'-guanosine 18%
• Tumor Suppressor Genes 11%
• Carcinogens 10%
• Tobacco 10%
• High Pressure Liquid Chromatography 9%
• Schiff Bases 8%
• Isotope Labeling 8%
• Acrolein 8%
• 5-Methylcytosine 7%
• Hypoxanthine Phosphoribosyltransferase 7%
• Epoxy Compounds 7%
• DNA Adducts 7%
• Benzo(a)pyrene 6%
• Frameshift Mutation 6%
• Oligodeoxyribonucleotides 6%
• Gastrointestinal Neoplasms 6%
• Guanine 6%
• Beverages 6%
• Laboratory Animals 6%
• Nucleosides 5%
• Reporter Genes 5%
• Mutagenesis 5%
• Point Mutation 5%
• Smoke 5%
• Respiratory System 5%
• Alcohol Drinking 5%
• Ethanol 4%
• Lung Neoplasms 4%
• Aptitude 3%
• Mutation 3%
• Neoplasms 1%

Chemical Compounds

• Acetaldehyde 34%
• Adduct 31%
• Dinucleotide 12%
• DNA Sequence 11%
• Mutation 9%
• 5-Methylcytosine 7%
• Acrolein 6%
• Benzo[a]pyrene 6%
• Smoke 6%
• Stable Isotope 6%
• Nucleobase 6%
• Guanine 5%
• Diol 5%
• Nucleoside 5%
• Reduction 5%
• Epoxide 4%
• Amino Groups 4%
• Schiff Base 4%
• Metabolite 3%
• Ethanol 3%
• Alcohol 3%
• Modification 3%