Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os

K. C. Scott; R. C. Hill; D. D. Lewis; R. Gronwall; D. A. Sundstrom; G. L. Jones; J. Harper

doi:10.1046/j.1439-0396.2002.00378.x

Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os

K. C. Scott, R. C. Hill, D. D. Lewis, R. Gronwall, D. A. Sundstrom, G. L. Jones, J. Harper

Statistics (Twin Cities)

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Abstract

Plasma vitamin C concentrations (mean + SD) were measured after a large (1 g) dose of vitamin C was administered orally or intravenously to each of four trained greyhounds in a randomized cross-over design. Concentrations increased (p < 0.05) for 2 h but returned to baseline by 6 h after supplementation. Peak concentrations were greater (p < 0.01) after intravenous than oral administration (6.1 ± 1.2 vs. 0.54 ± 0.23 mg/dl). This suggests that vitamin C must be administered many times daily to maintain plasma concentrations above normal.

Original language	English (US)
Pages (from-to)	222-228
Number of pages	7
Journal	Journal of Animal Physiology and Animal Nutrition
Volume	86
Issue number	7-8
DOIs	https://doi.org/10.1046/j.1439-0396.2002.00378.x
State	Published - 2002

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Scott, K. C., Hill, R. C., Lewis, D. D., Gronwall, R., Sundstrom, D. A., Jones, G. L., & Harper, J. (2002). Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os. Journal of Animal Physiology and Animal Nutrition, 86(7-8), 222-228. https://doi.org/10.1046/j.1439-0396.2002.00378.x

Scott, KC, Hill, RC, Lewis, DD, Gronwall, R, Sundstrom, DA, Jones, GL & Harper, J 2002, 'Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os', Journal of Animal Physiology and Animal Nutrition, vol. 86, no. 7-8, pp. 222-228. https://doi.org/10.1046/j.1439-0396.2002.00378.x

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Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os

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