Sexual recombination in Aspergillus tubingensis

Rodrigo A. Olarte, Bruce W. Horn, Rakhi Singh, Ignazio Carbone

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Aspergillus tubingensis from section Nigri (black Aspergilli) is closely related to A. niger and is used extensively in the industrial production of enzymes and organic acids. We recently discovered sexual reproduction in A. tubingensis, and in this study we demonstrate that the progeny are products of meiosis. Progeny were obtained from six crosses involving five MAT1-1 strains and two MAT1-2 strains. We examined three loci, including mating type (MAT), RNA polymerase II (RPB2) and β-tubulin (BT2), and found that 84% (58/69) of progeny were recombinants. Recombination associated with sexual reproduction in A. tubingensis provides a new option for the genetic improvement of industrial strains for enzyme and organic acid production.

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
Issue number2
StatePublished - 2015

Bibliographical note

Publisher Copyright:
© 2015 by The Mycological Society of America.


  • Aspergillus niger
  • Mating type
  • Multilocus sequence typing
  • Sexual reproduction


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