TY - JOUR
T1 - Short TE phosphorus spectroscopy using a spin‐echo pulse
AU - Lim, Kelvin O.
AU - Pauly, John
AU - Webb, Peter
AU - Hurd, Ralph
AU - Macovski, Albert
PY - 1994/7
Y1 - 1994/7
N2 - In vivo phosphorus spectroscopy requires very short acquisition delays in order to capture the signal from components with short transverse relaxation times (T2). The echo time typical of standard slice selective spin‐echo pulses are too long for this application, so hard pulse, free induction decay (FID) acquisitions have frequently been used instead. With FID, however, there is an interval between the time of coherence and data acquisition (acquisition delay), with resulting baseline distortions. In this paper we describe the design of a new short TE, slice‐selective, composite spin‐echo pulse with echo times as short as 2.5 ms. With a long TR, fully relaxed, multislice spectra can be collected. This technique will be useful for assessing, in vivo, changes in brain phospholipid activity associated with psychiatric and neurological diseases.
AB - In vivo phosphorus spectroscopy requires very short acquisition delays in order to capture the signal from components with short transverse relaxation times (T2). The echo time typical of standard slice selective spin‐echo pulses are too long for this application, so hard pulse, free induction decay (FID) acquisitions have frequently been used instead. With FID, however, there is an interval between the time of coherence and data acquisition (acquisition delay), with resulting baseline distortions. In this paper we describe the design of a new short TE, slice‐selective, composite spin‐echo pulse with echo times as short as 2.5 ms. With a long TR, fully relaxed, multislice spectra can be collected. This technique will be useful for assessing, in vivo, changes in brain phospholipid activity associated with psychiatric and neurological diseases.
KW - P
KW - spectroscopy
KW - spin‐echo pulse
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U2 - 10.1002/mrm.1910320113
DO - 10.1002/mrm.1910320113
M3 - Article
C2 - 8084242
AN - SCOPUS:0028290898
SN - 0740-3194
VL - 32
SP - 98
EP - 103
JO - Magnetic resonance in medicine
JF - Magnetic resonance in medicine
IS - 1
ER -