TY - JOUR
T1 - Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
AU - Martin, Christopher T
AU - Niewoehner, Catherine B
AU - Burmeister, Lynn A
PY - 2017/4/24
Y1 - 2017/4/24
N2 - We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings.
AB - We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings.
KW - Bone mineral density
KW - Immobilization
KW - Osteoporosis
KW - Teriparatide
UR - http://www.scopus.com/inward/record.url?scp=85065303266&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065303266&partnerID=8YFLogxK
U2 - 10.1210/js.2017-00049
DO - 10.1210/js.2017-00049
M3 - Article
C2 - 29264514
SN - 2472-1972
VL - 1
SP - 609
EP - 614
JO - Journal of the Endocrine Society
JF - Journal of the Endocrine Society
IS - 6
ER -