Some allylic substituent effects in ring-closing metathesis reactions: Allylic alcohol activation

Thomas R. Hoye, Hongyu Zhao

Research output: Contribution to journalArticlepeer-review

199 Scopus citations

Abstract

(matrix presented) Dienes 2a-e were used to study allylic substituent effects in the ring-closing metathesis reaction (RCM). Both the steric and electronic character of the allylic substituents were found to influence alkene reactivities. Free allylic hydroxyl groups exert a large activating effect on the RCM reaction rates.

Original languageEnglish (US)
Pages (from-to)1123-1125
Number of pages3
JournalOrganic Letters
Volume1
Issue number7
DOIs
StatePublished - Oct 7 1999

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