Spectroscopic and computational studies of (μ-Oxo)(μ-1, 2-peroxo)diiron(III) complexes of relevance to nonheme diiron oxygenase intermediates

Adam T. Fiedler, Xiaopeng Shan, Mark P. Mehn, József Kaizer, Stéphane Torelli, Jonathan R. Frisch, Masahito Kodera, Lawrence Que

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32 Scopus citations

Abstract

With the goal of gaining insight into the structures of peroxo intermediates observed for oxygen-activating nonheme diiron enzymes, a series of metastable synthetic diiron(III)-peroxo complexes with [FeIII 2(μ-O)(μ- 1, 2-O2)] cores has been characterized by X-ray absorption and resonance Raman spectroscopies, EXAFS analysis shows that this basic core structure gives rise to an Fe-Fe distance of ~3.15 Å; the distance is decreased by 0.1 Å upon introduction of an additional carboxylate bridge. In corresponding resonance Raman studies, vibrations arising from both the Fe-O-Fe and the Fe-O-O-Fe units can be observed. Importantly a linear correlation can be discerned between the v(O-O) frequency of a complex and its Fe-Fe distance among the subset of complexes with [FeIII 2(μ-OR)(μ-1, 2-O2)] cores (R = H, alkyl, aryl, or no substituent). These experimental studies are complemented by a normal coordinate analysis and DFT calculations.

Original languageEnglish (US)
Pages (from-to)13037-13044
Number of pages8
JournalJournal of Physical Chemistry A
Volume112
Issue number50
DOIs
StatePublished - Dec 18 2008

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