Speculations on the Role of Transmissible Agents in the Pathogenesis of Alzheimer's Disease

Ashley T. Haase; Elizabeth Lewis; Stephen Wietgrefe; Mary Zupancic; Diedrich Jane; Hal Minnigan; Melvyn J. Ball

doi:10.1017/S0317167100037100

Speculations on the Role of Transmissible Agents in the Pathogenesis of Alzheimer's Disease

Ashley T. Haase, Elizabeth Lewis, Stephen Wietgrefe, Mary Zupancic, Diedrich Jane, Hal Minnigan, Melvyn J. Ball

Microbiology

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4 Scopus citations

Abstract

Unconventional agents and conventional viruses provide model systems to investigate the pathogenesis of Alzheimer's disease (AD). The essay which follows examines the hypothetical role of herpes simplex in AD and presents some generally applicable experimental approaches to detecting genes in brain tissues. The concluding section, on parallels between AD and diseases of the brain caused by unconventional viruses, defines strategies for isolating genes related to pathology.

Original language	English (US)
Pages (from-to)	449-451
Number of pages	3
Journal	Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Volume	13
Issue number	S4
DOIs	https://doi.org/10.1017/S0317167100037100
State	Published - Nov 1986

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AU - Minnigan, Hal

AU - Ball, Melvyn J.

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Speculations on the Role of Transmissible Agents in the Pathogenesis of Alzheimer's Disease

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