Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil: A Case Report

J. Dawn Abbott; Jeptha P. Curtis; Khalil Murad; Harvey M. Kramer; Michael S. Remetz; John F. Setaro; Joseph J. Brennan

doi:10.1177/000331970305400613

Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil: A Case Report

J. Dawn Abbott, Jeptha P. Curtis, Khalil Murad, Harvey M. Kramer, Michael S. Remetz, John F. Setaro, Joseph J. Brennan

Medicine - Cardiology Division

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A 39-year-old woman with cervical cancer treated with pelvic radiation therapy and 5-fluorouracil (5-FU) was hospitalized for dehydration and intractable vomiting. She developed an acute ST-elevation myocardial infarction (MI) that extended electrocardiographically after thrombolytic therapy. Coronary angiography demonstrated a completely occluded left anterior descending (LAD) artery with extensive coronary dissection that was treated successfully with stenting. The authors discuss several factors that may have contributed to the spontaneous coronary artery dissection (SCAD) including chemotherapy-induced vasospasm, hemodynamic stress of vomiting, and hormonal changes associated with pelvic radiation.

Original language	English (US)
Pages (from-to)	721-724
Number of pages	4
Journal	Angiology
Volume	54
Issue number	6
DOIs	https://doi.org/10.1177/000331970305400613
State	Published - 2003

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1177/000331970305400613

OpenUrl availability

Full text

Cite this

@article{90e24c9fb83b430eba9a1ea6e6b93184,

title = "Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil: A Case Report",

abstract = "A 39-year-old woman with cervical cancer treated with pelvic radiation therapy and 5-fluorouracil (5-FU) was hospitalized for dehydration and intractable vomiting. She developed an acute ST-elevation myocardial infarction (MI) that extended electrocardiographically after thrombolytic therapy. Coronary angiography demonstrated a completely occluded left anterior descending (LAD) artery with extensive coronary dissection that was treated successfully with stenting. The authors discuss several factors that may have contributed to the spontaneous coronary artery dissection (SCAD) including chemotherapy-induced vasospasm, hemodynamic stress of vomiting, and hormonal changes associated with pelvic radiation.",

author = "Abbott, {J. Dawn} and Curtis, {Jeptha P.} and Khalil Murad and Kramer, {Harvey M.} and Remetz, {Michael S.} and Setaro, {John F.} and Brennan, {Joseph J.}",

year = "2003",

doi = "10.1177/000331970305400613",

language = "English (US)",

volume = "54",

pages = "721--724",

journal = "Angiology",

issn = "0003-3197",

publisher = "SAGE Publications Inc.",

number = "6",

}

TY - JOUR

T1 - Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil

T2 - A Case Report

AU - Abbott, J. Dawn

AU - Curtis, Jeptha P.

AU - Murad, Khalil

AU - Kramer, Harvey M.

AU - Remetz, Michael S.

AU - Setaro, John F.

AU - Brennan, Joseph J.

PY - 2003

Y1 - 2003

N2 - A 39-year-old woman with cervical cancer treated with pelvic radiation therapy and 5-fluorouracil (5-FU) was hospitalized for dehydration and intractable vomiting. She developed an acute ST-elevation myocardial infarction (MI) that extended electrocardiographically after thrombolytic therapy. Coronary angiography demonstrated a completely occluded left anterior descending (LAD) artery with extensive coronary dissection that was treated successfully with stenting. The authors discuss several factors that may have contributed to the spontaneous coronary artery dissection (SCAD) including chemotherapy-induced vasospasm, hemodynamic stress of vomiting, and hormonal changes associated with pelvic radiation.

AB - A 39-year-old woman with cervical cancer treated with pelvic radiation therapy and 5-fluorouracil (5-FU) was hospitalized for dehydration and intractable vomiting. She developed an acute ST-elevation myocardial infarction (MI) that extended electrocardiographically after thrombolytic therapy. Coronary angiography demonstrated a completely occluded left anterior descending (LAD) artery with extensive coronary dissection that was treated successfully with stenting. The authors discuss several factors that may have contributed to the spontaneous coronary artery dissection (SCAD) including chemotherapy-induced vasospasm, hemodynamic stress of vomiting, and hormonal changes associated with pelvic radiation.

UR - http://www.scopus.com/inward/record.url?scp=0345305775&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0345305775&partnerID=8YFLogxK

U2 - 10.1177/000331970305400613

DO - 10.1177/000331970305400613

M3 - Article

C2 - 14666962

AN - SCOPUS:0345305775

SN - 0003-3197

VL - 54

SP - 721

EP - 724

JO - Angiology

JF - Angiology

IS - 6

ER -

Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil: A Case Report

Abstract

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this