Abstract
STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4+ helper and regulatory T-cell subsets.
Original language | English (US) |
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Article number | 32 |
Journal | F1000Research |
Volume | 6 |
DOIs | |
State | Published - 2017 |
Bibliographical note
Funding Information:DLO is funded by a National Institutes of Health (NIH) T32 fellowship (T32 AI 007313). MAF is supported by grants from the NIH (R01 AI113138, R01 CA151845, R01 CA154998, and R01 CA185062).
Publisher Copyright:
© 2017 Owen DL and Farrar MA.
Keywords
- STAT5
- T-cell development
- T-cell function