Statins for hemodialysis patients with diabetes? Long-term follow-up endorses the original conclusions of the 4D Study

David C. Wheeler; Bertram L. Kasiske

doi:10.1016/j.kint.2016.02.045

Statins for hemodialysis patients with diabetes? Long-term follow-up endorses the original conclusions of the 4D Study

David C. Wheeler, Bertram L. Kasiske

Medicine - Renal and Hypertension Division

Research output: Contribution to journal › Comment/debate › peer-review

3 Scopus citations

Abstract

The clinical benefits of statins in dialysis patients are unproven. New follow-up data from the 4D Study indicate no clear reduction in cardiovascular events among patients with type-2 diabetes. Assessing outcomes 7.4 years beyond the randomization period (20 mg atorvastatin versus placebo), no differences in a composite cardiovascular outcome were observed and no safety concerns emerged. Current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines do not need updating based on these new data.

Original language	English (US)
Pages (from-to)	1189-1191
Number of pages	3
Journal	Kidney international
Volume	89
Issue number	6
DOIs	https://doi.org/10.1016/j.kint.2016.02.045
State	Published - 2016

Bibliographical note

Publisher Copyright:
© 2016 International Society of Nephrology

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abstract = "The clinical benefits of statins in dialysis patients are unproven. New follow-up data from the 4D Study indicate no clear reduction in cardiovascular events among patients with type-2 diabetes. Assessing outcomes 7.4 years beyond the randomization period (20 mg atorvastatin versus placebo), no differences in a composite cardiovascular outcome were observed and no safety concerns emerged. Current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines do not need updating based on these new data.",

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Statins for hemodialysis patients with diabetes? Long-term follow-up endorses the original conclusions of the 4D Study

Abstract

Bibliographical note

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