TY - JOUR
T1 - Statistical analysis and modeling of pelletized cultivation of Mucor circinelloides for microbial lipid accumulation
AU - Xia, Chunjie
AU - Wei, Wei
AU - Hu, Bo
PY - 2014/4
Y1 - 2014/4
N2 - Microbial oil accumulation via oleaginous fungi has some potential benefits because filamentous fungi can form pellets during cell growth and these pellets are easier to harvest from the culture broth than individual cells. This research studied the effect of various culture conditions on the pelletized cell growth of Mucor circinelloides and its lipid accumulation. The results showed that cell pelletization was positively correlated to biomass accumulation; however, pellet size was negatively correlated to the oil content of the fungal biomass, possibly due to the mass transfer barriers generated by the pellet structure. How to control the size of the pellet is the key to the success of the pelletized microbial oil accumulation process.
AB - Microbial oil accumulation via oleaginous fungi has some potential benefits because filamentous fungi can form pellets during cell growth and these pellets are easier to harvest from the culture broth than individual cells. This research studied the effect of various culture conditions on the pelletized cell growth of Mucor circinelloides and its lipid accumulation. The results showed that cell pelletization was positively correlated to biomass accumulation; however, pellet size was negatively correlated to the oil content of the fungal biomass, possibly due to the mass transfer barriers generated by the pellet structure. How to control the size of the pellet is the key to the success of the pelletized microbial oil accumulation process.
KW - Fungal pelletization
KW - Microbial lipid accumulation
KW - Mucor circinelloides
UR - http://www.scopus.com/inward/record.url?scp=84899419680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899419680&partnerID=8YFLogxK
U2 - 10.1007/s12010-014-0759-8
DO - 10.1007/s12010-014-0759-8
M3 - Article
C2 - 24549800
AN - SCOPUS:84899419680
SN - 0273-2289
VL - 172
SP - 3502
EP - 3512
JO - Applied Biochemistry and Biotechnology
JF - Applied Biochemistry and Biotechnology
IS - 7
ER -