Stereoselective synthesis of the C7-C21 segment of epothilone A via asymmetric alkoxyallyl- and crotylboration

P. Veeraraghavan Ramachandran; Bodhuri Prabhudas; Debarshi Pratihar; J. Subash Chandra; M. Venkat Ram Reddy

doi:10.1016/S0040-4039(03)00748-2

Stereoselective synthesis of the C₇-C₂₁ segment of epothilone A via asymmetric alkoxyallyl- and crotylboration

P. Veeraraghavan Ramachandran, Bodhuri Prabhudas, Debarshi Pratihar, J. Subash Chandra, M. Venkat Ram Reddy

Chemistry & Biochemistry

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The synthesis of the C₇-C₂₁ fragment of epothilone A involving asymmetric alkoxyallyl- and crotylboration using α-pinene-derived reagents is described.

Original language	English (US)
Pages (from-to)	3745-3748
Number of pages	4
Journal	Tetrahedron Letters
Volume	44
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(03)00748-2
State	Published - May 5 2003

Bibliographical note

Funding Information:
Financial support from the Herbert C. Brown Center for Borane Research and Aldrich Chemical Company is greatly acknowledged.

Keywords

Alkoxyallylboration
Crotylboration
Epothilone
Wittig reaction
α-pinene

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10.1016/S0040-4039(03)00748-2

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title = "Stereoselective synthesis of the C7-C21 segment of epothilone A via asymmetric alkoxyallyl- and crotylboration",

abstract = "The synthesis of the C7-C21 fragment of epothilone A involving asymmetric alkoxyallyl- and crotylboration using α-pinene-derived reagents is described.",

keywords = "Alkoxyallylboration, Crotylboration, Epothilone, Wittig reaction, α-pinene",

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note = "Funding Information: Financial support from the Herbert C. Brown Center for Borane Research and Aldrich Chemical Company is greatly acknowledged. ",

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T1 - Stereoselective synthesis of the C7-C21 segment of epothilone A via asymmetric alkoxyallyl- and crotylboration

AU - Ramachandran, P. Veeraraghavan

AU - Prabhudas, Bodhuri

AU - Pratihar, Debarshi

AU - Chandra, J. Subash

AU - Reddy, M. Venkat Ram

N1 - Funding Information: Financial support from the Herbert C. Brown Center for Borane Research and Aldrich Chemical Company is greatly acknowledged.

PY - 2003/5/5

Y1 - 2003/5/5

N2 - The synthesis of the C7-C21 fragment of epothilone A involving asymmetric alkoxyallyl- and crotylboration using α-pinene-derived reagents is described.

AB - The synthesis of the C7-C21 fragment of epothilone A involving asymmetric alkoxyallyl- and crotylboration using α-pinene-derived reagents is described.

KW - Alkoxyallylboration

KW - Crotylboration

KW - Epothilone

KW - Wittig reaction

KW - α-pinene

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