Strategies to retain participants in a long-term HIV prevention randomized controlled trial: Lessons from the MINTS-II study

Keith J. Horvath, Kate Nygaard, Gene P. Danilenko, Sinan Goknur, J. Michael Oakes, B. R. Simon Rosser

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Achieving satisfactory retention in online HIV prevention trials typically has proven difficult, particularly over extended timeframes. The overall aim of this study was to assess factors associated with retention in the Men's INTernet Study II (MINTS-II), a randomized controlled trial of a sexual risk reduction intervention for men who have sex with men. Participants were recruited via e-mails and banner advertisements in December, 2007 to participate in the MINTS-II Sexpulse intervention and followed over a 12-month period. Retention across the treatment and control arms was 85.2% at 12 months. Factors associated with higher retention included: randomization to the control arm, previous participation in a study by the research team, e-mail and telephone reminders to complete a survey once it was available online, and fewer e-mail contacts between surveys. The results provide evidence that achieving satisfactory retention is possible in online HIV prevention trials, and suggest best practices for maximizing retention.

Original languageEnglish (US)
Pages (from-to)469-479
Number of pages11
JournalAIDS and Behavior
Volume16
Issue number2
DOIs
StatePublished - Feb 2012

Bibliographical note

Funding Information:
Acknowledgement Funding for this study was provided by the National Institute of Mental Health (grant 5 R01 MH063688-05). We express our appreciation to the study participants for their time and effort devoted to this research.

Keywords

  • Internet
  • Men who have sex with men
  • Randomized controlled trial
  • Retention

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