Structural "snapshots" along reaction pathways of non-heme iron enzymes

Joseph P. Emerson; Erik R. Farquhar; Lawrence Que

doi:10.1002/anie.200703057

Structural "snapshots" along reaction pathways of non-heme iron enzymes

Joseph P. Emerson, Erik R. Farquhar, Lawrence Que

Chemistry (Twin Cities)

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Recent X-ray crystallography studies on two non-heme iron enzymes (see picture, orange Fe, red O, blue N) involved in oxygen activation and superoxide detoxification have provided unique structural insights into intermediates in their individual reaction pathways. The results of these studies and their mechanistic significance are discussed. (Figure Presented).

Original language	English (US)
Pages (from-to)	8553-8556
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	45
DOIs	https://doi.org/10.1002/anie.200703057
State	Published - 2007

Keywords

Bioinorganic chemistry
Metalloenzymes
Non-heme iron complexes
Oxygen activation
Superoxide reductase

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abstract = "Recent X-ray crystallography studies on two non-heme iron enzymes (see picture, orange Fe, red O, blue N) involved in oxygen activation and superoxide detoxification have provided unique structural insights into intermediates in their individual reaction pathways. The results of these studies and their mechanistic significance are discussed. (Figure Presented).",

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AU - Farquhar, Erik R.

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KW - Non-heme iron complexes

KW - Oxygen activation

KW - Superoxide reductase

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Structural "snapshots" along reaction pathways of non-heme iron enzymes

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Keywords

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