This chapter reviews our study of Morita-Baylis-Hillman (MBH) and vinylmetalation reactions for the synthesis of achiral and chiral, functionalized, fluorinated allyl alcohols. Vinylmetalation of fluoro-carbonyls with aluminum and copper reagents for the synthesis of unsubstituted, and β-substituted fluorinated allyl alcohols is summarized. An exploratory study of terpenyl alcohols as chiral auxiliaries in these reactions is also discussed.
|Original language||English (US)|
|Number of pages||10|
|Journal||ACS Symposium Series|
|State||Published - Dec 1 1999|