Successful Treatment of Human Acute T-Cell Leukemia in SCID Mice Using the Anti-CD7-deglycosylated Ricin A-Chain Immunotoxin DA7

Medicine & Life Sciences

• DA7 immunotoxin 100%
• Ricin 59%
• Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 55%
• SCID Mice 49%
• Leukemia 23%
• Immunotoxins 18%
• Animals 14%
• Precursor Cell Lymphoblastic Leukemia-Lymphoma 13%
• Anti-Idiotypic Antibodies 11%
• T-Cell Leukemia 9%
• Injections 8%
• Peritoneum 7%
• Survival 7%
• T-Cell Antigen Receptor 7%
• Therapeutics 6%
• Nude Mice 6%
• Melanoma 5%
• Therapeutic Uses 5%
• Cell Line 4%
• In Vitro Techniques 3%
• Proteins 2%
• Neoplasms 2%