1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 31 kDa human galectin-7 (p53-induced gene 1) homodimer, a pro-apoptotic lectin

Irina V. Nesmelova, Manuel Álvaro Berbís, Michelle C. Miller, F. Javier Cañada, Sabine André, Jesús Jiménez-Barbero, Hans Joachim Gabius, Kevin H. Mayo

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Galectins are multifunctional proteins with carbohydrate/protein-binding properties and distinct expression profiles. Homodimeric galectin-7 (p53-induced gene 1) is a potent pro-apoptotic effector with clinical relevance. Here, we report 1H, 13C, and 15N chemical shift assignments for human galectin-7 dimer as determined by using heteronuclear, triple resonance NMR spectroscopy.

Original languageEnglish (US)
Pages (from-to)127-129
Number of pages3
JournalBiomolecular NMR Assignments
Volume6
Issue number2
DOIs
StatePublished - Oct 2012

Bibliographical note

Funding Information:
Acknowledgments This work was made possible by a research grant from the National Cancer Institute (CA-096090) to KHM. NMR instrumentation was provided with funds from the National Science Foundation (BIR-961477), the University of Minnesota Medical School, and the Minnesota Medical Foundation.

Keywords

  • Apoptosis
  • Galectin
  • Glycan
  • Lectin
  • Proliferation

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