1H, 13C and 15N backbone and side-chain chemical shift assignments for the 29 kDa human galectin-1 protein dimer

Irina V. Nesmelova; Mabel Pang; Linda G. Baum; Kevin H. Mayo

doi:10.1007/s12104-008-9121-9

¹H, ¹³C and ¹⁵N backbone and side-chain chemical shift assignments for the 29 kDa human galectin-1 protein dimer

Irina V. Nesmelova, Mabel Pang, Linda G. Baum, Kevin H. Mayo

Chemical and Structural Biology (TMED)

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Galectin-1 is an important regulator of leukocyte function and tumor angiogenesis. Recently, this lectin has been identified as a molecular target for the potent angiogenesis inhibitor anginex. Here, we report ¹H, ¹³C and ¹⁵N chemical shift assignments for human galectin-1 as determined by using heteronuclear triple resonance NMR spectroscopy.

Original language	English (US)
Pages (from-to)	203-205
Number of pages	3
Journal	Biomolecular NMR Assignments
Volume	2
Issue number	2
DOIs	https://doi.org/10.1007/s12104-008-9121-9
State	Published - Dec 2008

Bibliographical note

Funding Information:
Acknowledgments This work was made possible by a research grant from the National Cancer Institute (CA-096090) to KHM and NIH NRSA training grant (HL 07062) to IVN. NMR instrumentation was provided with funds from the National Science Foundation (BIR-961477), the University of Minnesota Medical School, and the Minnesota Medical Foundation.

Keywords

Carbohydrate
Galactose
Galectin
NMR
Protein

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10.1007/s12104-008-9121-9

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Cite this

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title = "1H, 13C and 15N backbone and side-chain chemical shift assignments for the 29 kDa human galectin-1 protein dimer",

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AU - Pang, Mabel

AU - Baum, Linda G.

AU - Mayo, Kevin H.

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