Surgery of the Subthalamic Nucleus: Use of Movement-related Neuronal Activity for Surgical Navigation

Philip A. Starr, Philip V. Theodosopoulos, Robert Turner, Patrick J. Kelly, Kenneth B. Baker, Ali R. Rezai, Andres M. Lozano

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

The BASAL GANGLIA have important roles in somatic motor, oculomotor, limbic, and associative functions. These functions are represented in anatomically distinct territories in each basal ganglion nucleus. During surgery of the subthalamic nucleus for Parkinson's disease, the primary goal is to influence the physiology of the motor territory without affecting nonmotor areas. This article describes the use of movement-related cellular activity during single-unit microelectrode mapping to identify and to navigate within the motor territory of the subthalamic nucleus.

Original languageEnglish (US)
Pages (from-to)1146-1149
Number of pages4
JournalNeurosurgery
Volume53
Issue number5
DOIs
StatePublished - Nov 2003

Keywords

  • Basal ganglia
  • Deep brain stimulation
  • Motor circuits
  • Parkinson's disease
  • Subthalamic nucleus
  • Thalamocortical loops

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