Surgery of the Subthalamic Nucleus: Use of Movement-related Neuronal Activity for Surgical Navigation

Philip A. Starr; Philip V. Theodosopoulos; Robert Turner; Patrick J. Kelly; Kenneth B. Baker; Ali R. Rezai; Andres M. Lozano

doi:10.1227/01.NEU.0000088803.79153.05

Surgery of the Subthalamic Nucleus: Use of Movement-related Neuronal Activity for Surgical Navigation

Philip A. Starr, Philip V. Theodosopoulos, Robert Turner, Patrick J. Kelly, Kenneth B. Baker, Ali R. Rezai, Andres M. Lozano

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

The BASAL GANGLIA have important roles in somatic motor, oculomotor, limbic, and associative functions. These functions are represented in anatomically distinct territories in each basal ganglion nucleus. During surgery of the subthalamic nucleus for Parkinson's disease, the primary goal is to influence the physiology of the motor territory without affecting nonmotor areas. This article describes the use of movement-related cellular activity during single-unit microelectrode mapping to identify and to navigate within the motor territory of the subthalamic nucleus.

Original language	English (US)
Pages (from-to)	1146-1149
Number of pages	4
Journal	Neurosurgery
Volume	53
Issue number	5
DOIs	https://doi.org/10.1227/01.NEU.0000088803.79153.05
State	Published - Nov 2003
Externally published	Yes

Keywords

Basal ganglia
Deep brain stimulation
Motor circuits
Parkinson's disease
Subthalamic nucleus
Thalamocortical loops

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abstract = "The BASAL GANGLIA have important roles in somatic motor, oculomotor, limbic, and associative functions. These functions are represented in anatomically distinct territories in each basal ganglion nucleus. During surgery of the subthalamic nucleus for Parkinson's disease, the primary goal is to influence the physiology of the motor territory without affecting nonmotor areas. This article describes the use of movement-related cellular activity during single-unit microelectrode mapping to identify and to navigate within the motor territory of the subthalamic nucleus.",

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AU - Kelly, Patrick J.

AU - Baker, Kenneth B.

AU - Rezai, Ali R.

AU - Lozano, Andres M.

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Surgery of the Subthalamic Nucleus: Use of Movement-related Neuronal Activity for Surgical Navigation

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