Survival curves subjected to occasional insults

D. Zelterman, J. W. Curtsinger

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We describe a parametric family of survival curves, which can be used to model time to event data in systems subjected to occasional insults or shocks. Parameters control the location, magnitude, and durations of the effect for each insult. We use these models to describe the survival history of a large cohort of Drosophila that were transferred to new vials, on a weekly basis, as their nutrient medium deteriorated. A periodic model with lower parameters exhibits a good fit to the data.

Original languageEnglish (US)
Pages (from-to)1140-1146
Number of pages7
JournalBiometrics
Volume51
Issue number3
DOIs
StatePublished - 1995

Keywords

  • Drosophila melanogaster
  • Hazard function
  • Periodicity
  • Smooth models

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