Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain

Medicine & Life Sciences

• human HINT1 protein 100%
• Fluorescent Dyes 46%
• Neuralgia 46%
• Opioid Analgesics 39%
• Fluorescence 36%
• Nucleosides 23%
• histidine-binding protein 23%
• Catalytic Domain 20%
• Nucleotides 17%
• High-Throughput Screening Assays 15%
• indole 14%
• Dissociative Disorders 14%
• Psychology Transfer 13%
• Histidine 12%
• Central Nervous System Diseases 12%
• Tryptophan 11%
• Carrier Proteins 9%
• Psychological Inhibition 9%
• Schizophrenia 9%
• Electrons 8%
• Ligands 7%
• Water 7%
• Pain 6%
• Proteins 4%
• Therapeutics 3%

Physics & Astronomy

• pain 63%
• histidine 62%
• nucleotides 55%
• switches 36%
• proteins 35%
• probes 26%
• nucleosides 22%
• fluorescence 21%
• inhibitors 17%
• schizophrenia 12%
• indoles 11%
• central nervous system 10%
• life (durability) 10%
• tryptophan 9%
• electron transfer 7%
• ligands 7%
• screening 6%
• dissociation 6%
• disorders 5%
• rings 5%
• water 4%
• cells 3%
• molecules 3%

Chemical Compounds

• Histidine 42%
• Nucleotide 36%
• Probe 27%
• Protein 18%
• Nucleoside 13%
• Fluorescence 8%
• Tryptophan Residue 8%
• High Throughput Screening 7%
• Fluorescence Lifetime 7%
• Dissociation Constant 6%
• Indole 6%
• Fluorescence Intensity 6%
• Disorder 6%
• Displacement 6%
• Water Soluble 5%
• Electron Transfer 5%
• Ligand 3%
• Molecule 2%