Symptomatic congenital aortic stenosis in the first year of life

James H. Moller, Ahmad Nakib, Robert S. Eliot, Jesse E. Edwards

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

A clinical review of 18 cases of congenital aortic valvular stenosis symptomatic in thefirst year of life was undertaken. The electrocardiogram and thoracic roentgenograms mimic primary endocardial fibroelastosis; auscultatory findings, however, are usually sufficiently localized as to suggest aortic stenosis. Mitral insufficiency was a common finding in left ventriculograms. Pathologic study suggests that infants with aortic stenosis who are symptomatic in the first year of life commonly exhibit infarction of the left ventricular papillary muscles. This, in turn, is a fundamental cause of mitral regurgitation, a factor which may contribute to congestive cardiac failure.

Original languageEnglish (US)
Pages (from-to)728-734
Number of pages7
JournalThe Journal of pediatrics
Volume69
Issue number5 PART 1
DOIs
StatePublished - Nov 1966

Bibliographical note

Funding Information:
This study was supported by Public Health Service Research Grant HE-5694 and Research Training Grant 5 T1 HE 5570 of the National Heart Institute.

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