Synthesis, antiinflammatory and antibacterial activities of substituted 10H-indolo[3,2-b]quinoxalines

J. Thomas Leonard; O. S. Rajesh; K. Murugesh; V. Gunasekaran

Synthesis, antiinflammatory and antibacterial activities of substituted 10H-indolo[3,2-b]quinoxalines

J. Thomas Leonard, O. S. Rajesh, K. Murugesh, V. Gunasekaran

Research output: Contribution to journal › Article › peer-review

Abstract

A new series of fused quinoxalines as indoloquinoxalines were synthesized by condensing the appropriate isatin and o-phenylenediamine. N-Mannich bases of 10H-indoloquinoxalines (1-9) were synthesized by reacting formaldehyde and various secondary amines with indolo[3,2-b]quinoxaline. These compounds produced good antibacterial and anti-inflammatory activities.

Original language	English (US)
Pages (from-to)	2669-2673
Number of pages	5
Journal	Asian Journal of Chemistry
Volume	17
Issue number	4
State	Published - 2005
Externally published	Yes

Keywords

Indolo[3,2-b]quinoxaline
Mannich bases
Synthesis

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title = "Synthesis, antiinflammatory and antibacterial activities of substituted 10H-indolo[3,2-b]quinoxalines",

abstract = "A new series of fused quinoxalines as indoloquinoxalines were synthesized by condensing the appropriate isatin and o-phenylenediamine. N-Mannich bases of 10H-indoloquinoxalines (1-9) were synthesized by reacting formaldehyde and various secondary amines with indolo[3,2-b]quinoxaline. These compounds produced good antibacterial and anti-inflammatory activities.",

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language = "English (US)",

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T1 - Synthesis, antiinflammatory and antibacterial activities of substituted 10H-indolo[3,2-b]quinoxalines

AU - Leonard, J. Thomas

AU - Rajesh, O. S.

AU - Murugesh, K.

AU - Gunasekaran, V.

PY - 2005

Y1 - 2005

N2 - A new series of fused quinoxalines as indoloquinoxalines were synthesized by condensing the appropriate isatin and o-phenylenediamine. N-Mannich bases of 10H-indoloquinoxalines (1-9) were synthesized by reacting formaldehyde and various secondary amines with indolo[3,2-b]quinoxaline. These compounds produced good antibacterial and anti-inflammatory activities.

AB - A new series of fused quinoxalines as indoloquinoxalines were synthesized by condensing the appropriate isatin and o-phenylenediamine. N-Mannich bases of 10H-indoloquinoxalines (1-9) were synthesized by reacting formaldehyde and various secondary amines with indolo[3,2-b]quinoxaline. These compounds produced good antibacterial and anti-inflammatory activities.

KW - Indolo[3,2-b]quinoxaline

KW - Mannich bases

KW - Synthesis

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JO - Asian Journal of Chemistry

JF - Asian Journal of Chemistry

IS - 4

ER -

Synthesis, antiinflammatory and antibacterial activities of substituted 10H-indolo[3,2-b]quinoxalines

Abstract

Keywords

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