Synthesis of 2-(3-aryl-4-formylpyrazol-1-yl)-3-phenyl-1,8-naphthyridines

J. Sudhakar Rao, K. Mogilaiah, B. Sreenivasulu

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6 Scopus citations

Abstract

2-(3-Aryl-4-formylpyrazol-1-yl)-3-phenyl-1,8-naphthyridines (3) have been synthesized by the reaction of acetophenone 3-phenyl-1,8-naphthyridin-2-ylhydrazones (2) with POCl3 and DMF. The intermediate hydrazones 2 in turn are prepared by the condensation of 2-hydrazino-3-phenyl-1,8-naphthyridine (1) with different acetophenones. 1,8-Naphthyridines 3 have been characterized on the basis of their elemental analyses and spectral (IR, 1H NMR and mass) data and tested for their antibacterial activity.

Original languageEnglish (US)
Pages (from-to)713-714
Number of pages2
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume35
Issue number7
StatePublished - Jul 1 1996
Externally publishedYes

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