2-(3-Aryl-4-formylpyrazol-1-yl)-3-phenyl-1,8-naphthyridines (3) have been synthesized by the reaction of acetophenone 3-phenyl-1,8-naphthyridin-2-ylhydrazones (2) with POCl3 and DMF. The intermediate hydrazones 2 in turn are prepared by the condensation of 2-hydrazino-3-phenyl-1,8-naphthyridine (1) with different acetophenones. 1,8-Naphthyridines 3 have been characterized on the basis of their elemental analyses and spectral (IR, 1H NMR and mass) data and tested for their antibacterial activity.
|Original language||English (US)|
|Number of pages||2|
|Journal||Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry|
|State||Published - Jul 1 1996|