Synthesis of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by microwave assisted buchwald-hartwig amination

C. Kishor Kumar; H. Vijay Kumar; Nagaraja Naik

doi:10.1155/2011/851935

Synthesis of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by microwave assisted buchwald-hartwig amination

C. Kishor Kumar, H. Vijay Kumar, Nagaraja Naik

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

Abstract

An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.

Original language	English (US)
Pages (from-to)	1108-1113
Number of pages	6
Journal	E-Journal of Chemistry
Volume	8
Issue number	3
DOIs	https://doi.org/10.1155/2011/851935
State	Published - Jul 2011

Keywords

2-(2'-Di-tert- butylphosphine) biphenylpalladium(II) acetate
Buchwald-Hartwig amination
N-methyl-6-heterocyclic-1-oxoisoindoline
Synthesis

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title = "Synthesis of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by microwave assisted buchwald-hartwig amination",

abstract = "An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.",

keywords = "2-(2'-Di-tert- butylphosphine) biphenylpalladium(II) acetate, Buchwald-Hartwig amination, N-methyl-6-heterocyclic-1-oxoisoindoline, Synthesis",

author = "{Kishor Kumar}, C. and {Vijay Kumar}, H. and Nagaraja Naik",

year = "2011",

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KW - Buchwald-Hartwig amination

KW - N-methyl-6-heterocyclic-1-oxoisoindoline

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Synthesis of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by microwave assisted buchwald-hartwig amination

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Keywords

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