Abstract
The Richman-Atkins cyclization remains one of the most widely used methods for the preparation of macrocyclic polyamines. The use of β-trimethylsilylethanesulfonamides (SES-sulfonamides) for the preparation of polyazamacrocyclic compounds is described. This expands existing Richman-Atkins sulfonamide macrocyclization methodology, and it successfully enables preparation of labile polyaza[n](1,4)naphthalenophanes and polyaza[n](9,10)anthracenophanes, not previously available in appreciable quantities.
Original language | English (US) |
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Pages (from-to) | 2722-2725 |
Number of pages | 4 |
Journal | Journal of Organic Chemistry |
Volume | 66 |
Issue number | 8 |
DOIs | |
State | Published - Apr 20 2001 |