Synthesis of tobacco-specific N-nitrosamines and their metabolites and results of related bioassays

Medicine & Life Sciences

• 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid 87%
• Nitrosamines 82%
• N'-nitrosonornicotine 64%
• Biological Assay 63%
• 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol 58%
• Tobacco 57%
• N-Nitrosopyrrolidine 45%
• Dimethylnitrosamine 34%
• N'-nitrosoanabasine 25%
• N'-nitrosoanatabine 25%
• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol 21%
• 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 18%
• 1-Butanol 16%
• Cricetinae 12%
• Carcinogens 11%
• Smoke 11%
• Tobacco Products 11%
• Carcinogenesis 9%
• Lung 6%

Chemical Compounds

• N-Nitrosopyrrolidine 100%
• N-Nitrosodimethylamine 90%
• Bioassay 58%
• 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol 55%
• Metabolite 42%
• Butyric Acid 34%
• Smoke 34%