Systematic tuning of heme redox potentials and its effects on O₂ reduction rates in a designed oxidase in myoglobin

Medicine & Life Sciences

• Myoglobin 83%
• Heme 73%
• Oxidation-Reduction 63%
• Oxidoreductases 60%
• Electron Transport Complex IV 34%
• Cytochrome b Group 13%
• heme a 12%
• Diacetyl 11%
• Hemeproteins 11%
• Propionates 9%
• Hydrogen Bonding 8%
• Mutation 8%
• Histidine 8%
• Hydrophobic and Hydrophilic Interactions 8%
• Tyrosine 6%
• Catalytic Domain 6%
• Electrons 5%
• Ligands 5%
• Enzymes 4%

Engineering & Materials Science

• Oxidoreductases 100%
• Oxidation-Reduction 86%
• Tuning 51%
• Hemeproteins 29%
• Hydrogen bonds 18%
• Ligands 17%
• Hydrophobicity 17%
• Enzymes 15%
• Electrons 13%
• Substitution reactions 13%
• Catalysts 11%

Chemical Compounds

• Myoglobin 71%
• Redox Potential 63%
• Heme 61%
• Reduction 30%
• Cytochrome 19%
• Mutation 9%
• Propionate 6%
• Reduction Potential 5%
• Histidine 5%
• Tyrosine 5%
• Hydrophobicity 4%
• Sphere 4%
• Enzyme Activity 4%
• Substitution Reaction 3%
• Ligand 2%
• Catalyst 2%
• Protein 2%