TACAN Is an Ion Channel Involved in Sensing Mechanical Pain

Lou Beaulieu-Laroche; Marine Christin; Annmarie Donoghue; Francina Agosti; Noosha Yousefpour; Hugues Petitjean; Albena Davidova; Craig Stanton; Uzair Khan; Connor Dietz; Elise Faure; Tarheen Fatima; Amanda MacPherson; Stephanie Mouchbahani-Constance; Daniel G. Bisson; Lisbet Haglund; Jean A. Ouellet; Laura S. Stone; Jonathan Samson; Mary Jo Smith; Kjetil Ask; Alfredo Ribeiro-da-Silva; Rikard Blunck; Kate Poole; Emmanuel Bourinet; Reza Sharif-Naeini

doi:10.1016/j.cell.2020.01.033

TACAN Is an Ion Channel Involved in Sensing Mechanical Pain

Lou Beaulieu-Laroche, Marine Christin, Annmarie Donoghue, Francina Agosti, Noosha Yousefpour, Hugues Petitjean, Albena Davidova, Craig Stanton, Uzair Khan, Connor Dietz, Elise Faure, Tarheen Fatima, Amanda MacPherson, Stephanie Mouchbahani-Constance, Daniel G. Bisson, Lisbet Haglund, Jean A. Ouellet, Laura S. Stone, Jonathan Samson, Mary Jo SmithKjetil Ask, Alfredo Ribeiro-da-Silva, Rikard Blunck, Kate Poole, Emmanuel Bourinet, Reza Sharif-Naeini

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

Abstract

TACAN is identified as an ion channel that contributes to mechanosensitive currents in nociceptors and detecting mechanical pain stimuli.

Original language	English (US)
Pages (from-to)	956-967.e17
Journal	Cell
Volume	180
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2020.01.033
State	Published - Mar 5 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020

Keywords

TACAN
bilayer
ion channel
mechanosensitive
mechanotransduction
nociceptor
pain
patch clamp
pillar

Access

10.1016/j.cell.2020.01.033

OpenUrl availability

Full text

Cite this

Beaulieu-Laroche, L., Christin, M., Donoghue, A., Agosti, F., Yousefpour, N., Petitjean, H., Davidova, A., Stanton, C., Khan, U., Dietz, C., Faure, E., Fatima, T., MacPherson, A., Mouchbahani-Constance, S., Bisson, D. G., Haglund, L., Ouellet, J. A., Stone, L. S., Samson, J., ... Sharif-Naeini, R. (2020). TACAN Is an Ion Channel Involved in Sensing Mechanical Pain. Cell, 180(5), 956-967.e17. https://doi.org/10.1016/j.cell.2020.01.033

Beaulieu-Laroche, L, Christin, M, Donoghue, A, Agosti, F, Yousefpour, N, Petitjean, H, Davidova, A, Stanton, C, Khan, U, Dietz, C, Faure, E, Fatima, T, MacPherson, A, Mouchbahani-Constance, S, Bisson, DG, Haglund, L, Ouellet, JA, Stone, LS, Samson, J, Smith, MJ, Ask, K, Ribeiro-da-Silva, A, Blunck, R, Poole, K, Bourinet, E & Sharif-Naeini, R 2020, 'TACAN Is an Ion Channel Involved in Sensing Mechanical Pain', Cell, vol. 180, no. 5, pp. 956-967.e17. https://doi.org/10.1016/j.cell.2020.01.033

@article{cadf27918a8a4e1499a6d8ab048c3a18,

title = "TACAN Is an Ion Channel Involved in Sensing Mechanical Pain",

abstract = "TACAN is identified as an ion channel that contributes to mechanosensitive currents in nociceptors and detecting mechanical pain stimuli.",

keywords = "TACAN, bilayer, ion channel, mechanosensitive, mechanotransduction, nociceptor, pain, patch clamp, pillar",

author = "Lou Beaulieu-Laroche and Marine Christin and Annmarie Donoghue and Francina Agosti and Noosha Yousefpour and Hugues Petitjean and Albena Davidova and Craig Stanton and Uzair Khan and Connor Dietz and Elise Faure and Tarheen Fatima and Amanda MacPherson and Stephanie Mouchbahani-Constance and Bisson, {Daniel G.} and Lisbet Haglund and Ouellet, {Jean A.} and Stone, {Laura S.} and Jonathan Samson and Smith, {Mary Jo} and Kjetil Ask and Alfredo Ribeiro-da-Silva and Rikard Blunck and Kate Poole and Emmanuel Bourinet and Reza Sharif-Naeini",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = mar,

day = "5",

doi = "10.1016/j.cell.2020.01.033",

language = "English (US)",

volume = "180",

pages = "956--967.e17",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - TACAN Is an Ion Channel Involved in Sensing Mechanical Pain

AU - Beaulieu-Laroche, Lou

AU - Christin, Marine

AU - Donoghue, Annmarie

AU - Agosti, Francina

AU - Yousefpour, Noosha

AU - Petitjean, Hugues

AU - Davidova, Albena

AU - Stanton, Craig

AU - Khan, Uzair

AU - Dietz, Connor

AU - Faure, Elise

AU - Fatima, Tarheen

AU - MacPherson, Amanda

AU - Mouchbahani-Constance, Stephanie

AU - Bisson, Daniel G.

AU - Haglund, Lisbet

AU - Ouellet, Jean A.

AU - Stone, Laura S.

AU - Samson, Jonathan

AU - Smith, Mary Jo

AU - Ask, Kjetil

AU - Ribeiro-da-Silva, Alfredo

AU - Blunck, Rikard

AU - Poole, Kate

AU - Bourinet, Emmanuel

AU - Sharif-Naeini, Reza

PY - 2020/3/5

Y1 - 2020/3/5

N2 - TACAN is identified as an ion channel that contributes to mechanosensitive currents in nociceptors and detecting mechanical pain stimuli.

AB - TACAN is identified as an ion channel that contributes to mechanosensitive currents in nociceptors and detecting mechanical pain stimuli.

KW - TACAN

KW - bilayer

KW - ion channel

KW - mechanosensitive

KW - mechanotransduction

KW - nociceptor

KW - pain

KW - patch clamp

KW - pillar

UR - http://www.scopus.com/inward/record.url?scp=85080124491&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85080124491&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.01.033

DO - 10.1016/j.cell.2020.01.033

M3 - Article

C2 - 32084332

AN - SCOPUS:85080124491

SN - 0092-8674

VL - 180

SP - 956-967.e17

JO - Cell

JF - Cell

IS - 5

ER -

TACAN Is an Ion Channel Involved in Sensing Mechanical Pain

Abstract

Bibliographical note

Keywords

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this