Targeting T cells for GVHD therapy

Daniel A. Vallera

doi:10.1006/scbi.1996.0009

Targeting T cells for GVHD therapy

Daniel A. Vallera

Radiation Oncology

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Bone marrow transplantation is currently used to treat a variety of life-threatening diseases. Its applications could be expanded if the risks of graft-versus-host disease (GVHD), a complex pathologic disease, could be reduced. Immunotoxins may provide a means to control drug refractory GVHD. This article will discuss the development of immunotoxin approaches for either GVHD prevention or treatment, and explore their limitations.

Original language	English (US)
Pages (from-to)	57-64
Number of pages	8
Journal	Seminars in Cancer Biology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1006/scbi.1996.0009
State	Published - Apr 1996

Keywords

Bone marrow transplantation
Graft versus-host-disease
Immunotoxins
Mice
Therapy

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title = "Targeting T cells for GVHD therapy",

abstract = "Bone marrow transplantation is currently used to treat a variety of life-threatening diseases. Its applications could be expanded if the risks of graft-versus-host disease (GVHD), a complex pathologic disease, could be reduced. Immunotoxins may provide a means to control drug refractory GVHD. This article will discuss the development of immunotoxin approaches for either GVHD prevention or treatment, and explore their limitations.",

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KW - Mice

KW - Therapy

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Targeting T cells for GVHD therapy

Abstract

Keywords

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