TY - JOUR
T1 - Telangiectasia macularis eruptiva perstans
T2 - Report of three cases
AU - Tumer, Gizem
AU - Jow, Tiffany
AU - McElligott, Sean
AU - Schwartz, Robert A.
AU - Clark Lambert, W.
N1 - Publisher Copyright:
© 2017 Pulse Marketing & Communications, LLC.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Telangiectasia macularis eruptiva perstans (TMEP) is a rare, heterogeneous disease of mast cell proliferation. The variable clinical presentation of TMEP, coupled with its rarity, makes the recognition and diagnosis of this disease difficult and challenging for clinicians. The histopathologic findings with hematoxylin and eosin staining that distinguish TMEP from a normal skin biopsy can be so subtle that confirmation of the diagnosis with additional special stains (c-Kit, Giemsa, toluidine blue) is strongly recommended. We describe three cases that highlight the variable clinical presentation of TMEP. One patient experienced only a localized skin manifestation, another an aggressive clinical course with systemic involvement, and a third diffuse skin involvement with mild fatigue, muscle pain, and weight gain.
AB - Telangiectasia macularis eruptiva perstans (TMEP) is a rare, heterogeneous disease of mast cell proliferation. The variable clinical presentation of TMEP, coupled with its rarity, makes the recognition and diagnosis of this disease difficult and challenging for clinicians. The histopathologic findings with hematoxylin and eosin staining that distinguish TMEP from a normal skin biopsy can be so subtle that confirmation of the diagnosis with additional special stains (c-Kit, Giemsa, toluidine blue) is strongly recommended. We describe three cases that highlight the variable clinical presentation of TMEP. One patient experienced only a localized skin manifestation, another an aggressive clinical course with systemic involvement, and a third diffuse skin involvement with mild fatigue, muscle pain, and weight gain.
UR - http://www.scopus.com/inward/record.url?scp=85047246526&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047246526&partnerID=8YFLogxK
M3 - Article
C2 - 28705275
AN - SCOPUS:85047246526
SN - 1540-9740
VL - 15
SP - 171
EP - 174
JO - SKINmed
JF - SKINmed
IS - 3
ER -