TY - JOUR
T1 - Telehygiene System for Preventive Chronopharmacology in Space
AU - Halberg, Franz
AU - Cornelissen-Guillaume, Germaine G
AU - Bingham, Christopher
AU - del Pozo, Francisco
AU - Arredondo, Maria Teresa
AU - Otsuka, Kuniaki
AU - Quadens, Olga
AU - Breus, Tamara
AU - Rapoport, Semyon
AU - Komarov, Feodor
PY - 1994/6
Y1 - 1994/6
N2 - A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved. 1994 American College of Clinical Pharmacology
AB - A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved. 1994 American College of Clinical Pharmacology
UR - http://www.scopus.com/inward/record.url?scp=0028365458&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028365458&partnerID=8YFLogxK
U2 - 10.1002/j.1552-4604.1994.tb02006.x
DO - 10.1002/j.1552-4604.1994.tb02006.x
M3 - Article
C2 - 8083385
AN - SCOPUS:0028365458
SN - 0091-2700
VL - 34
SP - 552
EP - 557
JO - The Journal of Clinical Pharmacology
JF - The Journal of Clinical Pharmacology
IS - 6
ER -