Tetanus and Diphtheria Immunity in Urban Minnesota Adults

Kent Crossley, Patrick Irvine, J. Bryan Warren, Bryan K. Lee, Karen Mead

Research output: Contribution to journalArticlepeer-review

103 Scopus citations


Tetanus and diphtheria antitoxin levels were measured in 183 urban adults, using a hemagglutination technique. Protective levels (>0.01 unit/mL) of tetanus antitoxin were present in more than 85% of sera from all subjects under 40 years of age and from men between 40 and 59 years old. A minority of women (36%) between 40 and 59 years of age, and of men (41%) and women (29%) over 60 years of age, were protected. Less than one quarter of the study group had protective levels (>0.01 unit/mL) of diphtheria antitoxin. The results of this study suggest that a minority of middle-aged women and older adults have been appropriately immunized against diphtheria and tetanus.

Original languageEnglish (US)
Pages (from-to)2298-2300
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Issue number21
StatePublished - Nov 23 1979

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