Thalamic deep brain stimulation activates the cerebellothalamocortical pathway

G. F. Molnar, A. Sailer, C. A. Gunraj, A. E. Lang, A. M. Lozano, Robert Chen

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

To investigate the mechanism of action of deep brain stimulation (DBS), the authors studied the effects of thalamic DBS on the cerebellothalamocortical (CTC) pathway. With DBS turned off, excitability of the CTC pathway was reduced. Turning DBS on resulted in facilitation of the CTC pathway. Therefore, thalamic DBS appears to activate rather than inhibit the target area.

Original languageEnglish (US)
Pages (from-to)907-909
Number of pages3
JournalNeurology
Volume63
Issue number5
DOIs
StatePublished - Sep 14 2004

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