We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into genetically modified swine embryos and having human tissues produced in a pig's body transplanted into a human. This is greater acceptance than in Japan, and there is even strong acceptance among those with strong religious affiliations and who self-identify as conservatives. We argue that strong public support for HACE research, as well as the emerging literature suggesting that humanization of research animals is very unlikely, should compel the NIH to lift its current moratorium on HACE research.
Bibliographical noteFunding Information:
For helpful research assistance, we thank Jennifer Novo and Sydney Diekmann. The study was funded with internal University of Minnesota Law School faculty grant funding (to F.X.S.) and the University of Minnesota Brain Sciences Fund (to W.C.L.).
© 2020 The Authors
- US public attitudes
- blastocyst complementation
- ethics and policy
- gene editing
- human-animal chimeric embryo