The Biological Activity of Di-α-Tocopherone

D. J. Lee, H. H. Draper, J. G. Bergan, A. Saari Csallany

Research output: Contribution to journalArticlepeer-review

Abstract

Di-α-tocopherone, a recently characterized metabolite of α-tocopherol isolated from animal tissues, was tested for biological activity with respect to resorption-gestation in Vit. E-deficient rats, nutritional muscular dystrophy in rabbits and hereditary muscular dystrophy in mice. The results indicate that this metabolite has less than 5% of the Vit. E activity of α-tocopherol and that it possesses no therapeutic value in treatment of the congenital myopathy. Its probable role in metabolism is that of a terminal oxidation product rather than an active form of Vit. E.

Original languageEnglish (US)
Pages (from-to)242-245
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume113
Issue number1
DOIs
StatePublished - May 1963

Bibliographical note

Funding Information:
Supported by a grant from National Science Foundation.

Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.

Fingerprint Dive into the research topics of 'The Biological Activity of Di-α-Tocopherone'. Together they form a unique fingerprint.

Cite this