Summaryo1.Forty-two dogs underwent gastric pouch freezing, and gastric tissue temperature studies were done concomitantly in 27 dogs. In most cases, uniform temperature depression was observed using thermocouples at different locations on the balloon surface and within the same submucosal tissue plane of the pouch. The average balloon surface temperature was 3.4° colder than the mean submucosal temperature.2.The uniformity of temperatures is due in part to a high heat transfer coefficient or efficiency of the small round balloon used. The efficiency of the larger stomach-shaped balloon used in freezing the intact canine stomach is lower.3.In Group H B a tissue temperature of -2° to 4° C. maintained for 40 minutes produced an average achlorhydric period of 16.2 weeks (3 of 8 dogs are still achlorhydric at 16, 28 and 30 weeks). Doubling the duration of freezing from 20 to 40 minutes at these temperatures exerted a 2000 per cent increase in duration of the achlorhydria. These freezing conditions appear to be a safe limit for the intact stomach. Methods to improve the efficiency of freezing of the intact stomach are being studied.
Bibliographical noteFunding Information:
From the Department of Surgery, ,University of Minnesota Hospitals. Minneapolis, Minnesota, 55455. Supported by a U.S. Public Health Service Grant. the John A~ Hartford Foundat;.on and lhe Donald J. Cowling Fund for Surgic~fl Research~ Submitted for publication March 19. 1965,