The effect of phosphocreatine on reflex transmission in the spinal cord was studied in rats in vivo and in vitro. Low concentrations (10(-8)-10(-6) M) of phosphocreatine facilitated while high concentrations (10(-4)-10(-3) M) inhibited the amplitude of mono- and polysynaptic reflexes. It was found that phosphocreatine decreases the inhibiting action of hypoxia on test responses and accelerates restoration of the reflex transmission in the spinal cord.
|Translated title of the contribution||The effect of creatine phosphate on reflex transmission in the normal spinal cord and under hypoxic conditions|
|Number of pages||4|
|Journal||Zhurnal Voprosy Nejrokhirurgii Imeni N.N. Burdenko|
|State||Published - Jul 1 1990|