Abstract
We describe 19 males with Aarskog syndrome who were treated with growth hormone (GH) and enrolled in the National Cooperative Growth Study (NCGS). There was a significant increase in both growth rate (3.9±1.9 cm/yr vs 8.9±1.7 cm/yr, p<0.001) and height SD score (change in HtSDS=1.0±0.8). The increase in HtSDS was dependent on treatment duration, frequency of injections, weight-for-height SDS, and HtSDS at enrollment. The results of our study suggest a positive effect of GH treatment on growth and adult height in Aarskog syndrome patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 161-165 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Endocrinology and Metabolism |
| Volume | 12 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1999 |
Keywords
- Aarskog
- Facial-digital-genital
- Growth hormone
- Stature
- Syndrome