Abstract
Fifteen patients with chronic renal failure had depressed neutrophil chemotactic responsiveness following several hemodialysis treatments. The chemotactic index (C.I.) of these patients was 12.7 ± 6.4 as compared with 72.8 ± 22.7 for controls (p < 0.001). Patients with chronic renal failure, not on hemodialysis, had only mildly depressed neutrophil chemotactic responsiveness (42.3 ± 15; p < 0.01). Thus, hemodialysis impairs neutrophil function and may contribute to the increased risk of infection in uremic patients. Chemotactic responsiveness returned to normal in three patients following renal transplantation.
Original language | English (US) |
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Pages (from-to) | 971-974 |
Number of pages | 4 |
Journal | The Journal of laboratory and clinical medicine |
Volume | 88 |
Issue number | 6 |
State | Published - Dec 1976 |