The effects of clomipramine hydrochloride in cats with psychogenic alopecia: A prospective study

Petra A. Mertens, Sheila Torres, Carl Jessen

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A double-blind, placebo-controlled clinical trial was conducted to determine the efficacy of clomipramine hydrochloride in cats with psychogenic alopecia. Twenty-five cats were randomly assigned to receive clomipramine hydrochloride (0.5 mg/kg orally q 24 hours) or placebo for 56 days. Eleven cats in each group completed the trial. The results of this study showed that clomipramine hydrochloride failed to demonstrate significant changes in the number of grooming bouts, hair regrowth, and the area of alopecia in cats with psychogenic alopecia when compared to a placebo. It was uncertain whether these results reflected a lack of drug efficacy, insufficient treatment duration, or an insufficient number of cases enrolled.

Original languageEnglish (US)
Pages (from-to)336-343
Number of pages8
JournalJournal of the American Animal Hospital Association
Volume42
Issue number5
DOIs
StatePublished - Jan 1 2006

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