The first synthesis of a diynone from Echinacea pallida

George A. Kraus, Jaehoon Bae, Jessica Schuster

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


In order to provide an authentic standard and to generate pure material for biological testing, an efficient synthetic route to 1 was developed. This represents the first total synthesis of a major bioactive diynone from E. pallida.

Original languageEnglish (US)
Article numberM01805SS
Pages (from-to)3502-3504
Number of pages3
Issue number20
StatePublished - Dec 20 2005
Externally publishedYes


  • Coupling reaction
  • Diynones
  • Selective alkyne reduction
  • Selective desilylation

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